Morphine commonly causes which ocular effect?

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Study for the INBDE Pharmacology Test. Use flashcards and multiple-choice questions with hints and explanations to prepare for the exam effectively. Boost your confidence and ensure success on test day!

Multiple Choice

Morphine commonly causes which ocular effect?

Explanation:
Opioids like morphine commonly cause miosis, a pinching of the pupil to a small, constricted size. This happens because opioids increase parasympathetic outflow to the pupillary sphincter via mu-receptor activity, leading to pupil constriction. Clinically, pinpoint pupils are a classic sign of opioid effect or overdose. In contrast, dilation (mydriasis) occurs with sympathetic activation or anticholinergic effects, not with morphine; ptosis and nystagmus aren’t typical features of opioid-induced eye changes.

Opioids like morphine commonly cause miosis, a pinching of the pupil to a small, constricted size. This happens because opioids increase parasympathetic outflow to the pupillary sphincter via mu-receptor activity, leading to pupil constriction. Clinically, pinpoint pupils are a classic sign of opioid effect or overdose. In contrast, dilation (mydriasis) occurs with sympathetic activation or anticholinergic effects, not with morphine; ptosis and nystagmus aren’t typical features of opioid-induced eye changes.

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